B. Benhalima et al., TRANSESOPHAGEAL ECHOCARDIOGRAPHIC APPEARA NCES OF RUPTURED CHORDAE TENDINAE IN THE ELDERLY, Archives des maladies du coeur et des vaisseaux, 88(3), 1995, pp. 345-352
Ruptured mitral chordae tendinae is a classical complication of myxoma
tous mitral valves or Barlow's syndrome. This complication is controve
rsial in non-myxomatous mitral valve. Of 91 consecutive patients with
mitral valve prolapse examined over an 18 months period by transthorac
ic and transesophageal echocardiography, 42 (18 women and 24 men) with
an average age of 76 +/- 8 years (60-93 years) had ruptured mitral ch
ordae tendinae. The thickness of the anterior mitral leaflet measured
at the distal third of the valve by transesophageal echocardiography e
nabled the identification of two groups of patients; group I:>3 mm (24
patients), average 4.8 +/- 0.8 mm and group II:less than or equal to
3 mm (18 patients), average 2.6 +/- 0.3 mm. The diameter of the mitral
ring and left atrium, the length of the anterior mitral leaflet, the
left ventricular end diastolic dimensions and fractional shortening, w
ere measured by transthoracic 2D echocardiography (mitral ring) and M
mode (other parameters). Ruptured chordae were detected in only 13 cas
es (31%) by transthoracic echocardiography; 38% were asymptomatic and
a chance finding at transesophageal echocardiography. No significant d
ifference was observed between the two groups with respect to age, gen
der presence of hypertension, dimensions of the cardiac chambers, frac
tional shortening or localisation of the prolapse related to the ruptu
red chordae. Fifty-eight per cent of patients in group I were in NYHA
functional classes 3-4 as compared to 16% in group II(p<0.02). The siz
e of the left atrium was significantly greater in group I,51 +/- 8 mm
vs 38 +/- 7 mm (p<0.001). Two-dimensional color Doppler enabled differ
entiation between moderate and significant mitral regurgitation. Signi
ficant mitral regurgitation was more common in group I(p<0.02). Theref
ore, ruptured chordae tendinae is common in non-myxomatous mitral valv
e in the elderly, usually as an asymptomatic finding. Transesophageal
echocardiography is the diagnostic method of reference. The NYHA funct
ional class, left atrial and mitral ring dilatation, are associated wi
th mitral regurgitation of greater severity and are more common in chr
onic mitral regurgitation in myxomatous valves.