S. Mosebach et al., RHEUMATIC DISORDERS IN CROHNS-DISEASE AND ULCERATIVE-COLITIS INCIDENCE OF NONINFLAMMATORY FACTORS, Leber, Magen, Darm, 25(2), 1995, pp. 76
82 consecutive outpatients with Crohn's disease (n=52) and ulcerative
colitis (n=30) were examined ambulatory. Rheumatic complaints, objecti
ve results and diagnosis were correlated to the activity of the underl
ying illness and the extent of the bowel affected. 61% of the examined
patients complaint about rheumatic pains. In two thirds this could be
attributed to noninflammatory causes (30% insertion tendinitis, 16% d
egenerative arthritis, 16% wrong carriage), which appeared to be indep
endent of the activity and severity of the underlying disease. One fou
rth of the rheumatic complaints was caused by inflammation (21% arthri
tis, 5% sacroileitis). In these cases a dependency on the disease acti
vity and the extent of the colon involvement could be found. No cause
was found for 12% of the rheumatic complaints. In patients with ulcera
tive colitis suffering from arthritis a significant increase of diseas
e activity (Rachmilewitz index) could be shown as compared to ulcerati
ve colitis patients without arthritis (p<0.02). For patients with Croh
n's disease no significant correlation between arthritis and disease a
ctivity could be established. In these cases the occurrence of arthrit
is was associated with the colon involvement (Chi(2) = 8,48). The data
indicate the high frequency of rheumatic complaints in inflammatory b
owel diseases due to noninflammatory causes.