FAB MASS-SPECTROMETRY - CHARACTERIZATION OF A NEW CLASS OF AMPHIPHILIC DERIVATIVES OF 17-BETA-ESTRADIOL

Authors
DEBRAUWER L FOURNIER F PARIS A RAO D TABET JC
Citation
L. Debrauwer et al., FAB MASS-SPECTROMETRY - CHARACTERIZATION OF A NEW CLASS OF AMPHIPHILIC DERIVATIVES OF 17-BETA-ESTRADIOL, Analusis, 23(1), 1995, pp. 28-30
Citations number
15
Categorie Soggetti
Chemistry Analytical
Journal title
Analusis → ACNP
ISSN journal
03654877
Volume
23
Issue
1
Year of publication
1995
Pages
28 - 30
Database
ISI
SICI code
0365-4877(1995)23:1<28:FM-COA>2.0.ZU;2-Z
Abstract
Fast atom bombardment is used for the mass spectrometric characterizat ion of a new class of amphiphilic derivatives of 17 beta-estradiol. Th e choice of the matrix is discussed. Under negative ion conditions, th e deprotonated molecular ion is observed together with diagnostic frag ment ions. The molecular mass confirmation is achieved in the positive ion mode by cationisation with sodium.