ANTICOAGULANT FROM THE EXTRACT OF PEONY R ESTS - ISOLATION AND PROPERTIES

A protein-free anticoagulant preparation displaying anticoagulative bu t not fibrinolytic activity in vitro was isolated from peony. Electrop horetic, chromatographic, and spectral analyses revealed that this ant icoagulant resembles animal heparin: it contains sulfur, carbon, and n itrogen in quantities characteristic of the latter. Plant heparin enha nces anticoagulative and fibrinolytic plasma properties and decreases platelet aggregation. It may be used as a harmless and ecologically pu re anticoagulant.