CORRECTION OF ANEMIA AND THROMBOCYTOPENIA IN A CASE OF ADULT TYPE-I OSTEOPETROSIS WITH RECOMBINANT-HUMAN-ERYTHROPOIETIN (RHUEPO)

Authors
MELETIS J SAMARKOS M MICHALI E VAVOURAKIS S MELETIS C POZIOPOULOS C STAVROGIANNI N KONSTANTOPOULOS K VAIOPOULOS G YATAGANAS X LOUKOPOULOS D
Citation
J. Meletis et al., CORRECTION OF ANEMIA AND THROMBOCYTOPENIA IN A CASE OF ADULT TYPE-I OSTEOPETROSIS WITH RECOMBINANT-HUMAN-ERYTHROPOIETIN (RHUEPO), British Journal of Haematology, 89(4), 1995, pp. 911-913
Citations number
12
Categorie Soggetti
Hematology
Journal title
British Journal of Haematology → ACNP
ISSN journal
00071048
Volume
89
Issue
4
Year of publication
1995
Pages
911 - 913
Database
ISI
SICI code
0007-1048(1995)89:4<911:COAATI>2.0.ZU;2-8
Abstract
A case of adult osteopetrosis Type I was diagnosed in a 22-year-old fe male. She presented for investigation of anaemia with 'myelophthisic' characteristics and extramedullary haemopoiesis which was resistant to haematinics, nandrolone and low-dose corticosteroids. She became prog ressively transfusion-dependent with gradually worsening thrombocytope nia. She was successfully treated with recombinant erythropoietin. Ana emia as well as thrombocytopenia were corrected. There appeared to be a synergistic action of erythropoietin with steroids.