La. Killewich et al., SALVAGE OF RENAL-ALLOGRAFT FUNCTION AND LOWER-EXTREMITY VENOUS PATENCY WITH THROMBOLYTIC THERAPY - CASE-REPORT AND REVIEW OF THE LITERATURE, Journal of vascular surgery, 21(4), 1995, pp. 691-696
Five months after a cadaveric renal transplant a 69-year-old man was a
dmitted with caval, iliac, and renal allograft vein thrombosis that oc
curred in the setting of a previously placed caval filter. The patient
's urine output and renal function deteriorated rapidly. Thrombolytic
therapy with urokinase was begun, and lysis of the thrombus occurred i
n 72 hours. The patient's renal function returned to baseline, and the
transplant was salvaged. Moreover lower extremity venous patency and
valvular function were maintained. We report the case and review the l
iterature on thrombolytic therapy for renal allograft vein and lower e
xtremity deep venous thrombosis.