SALVAGE OF RENAL-ALLOGRAFT FUNCTION AND LOWER-EXTREMITY VENOUS PATENCY WITH THROMBOLYTIC THERAPY - CASE-REPORT AND REVIEW OF THE LITERATURE

Five months after a cadaveric renal transplant a 69-year-old man was a dmitted with caval, iliac, and renal allograft vein thrombosis that oc curred in the setting of a previously placed caval filter. The patient 's urine output and renal function deteriorated rapidly. Thrombolytic therapy with urokinase was begun, and lysis of the thrombus occurred i n 72 hours. The patient's renal function returned to baseline, and the transplant was salvaged. Moreover lower extremity venous patency and valvular function were maintained. We report the case and review the l iterature on thrombolytic therapy for renal allograft vein and lower e xtremity deep venous thrombosis.