Concepts and methods of laser labyrinthectomy have been proposed based
on experimental studies in which the macula utriculi was irradiated w
ith an argon laser beam through the oval window. In our previous repor
ts, a single application of the beam (1.5 W, 0.5 s) eradicated the gui
nea pig macula within 5 weeks. The contour of the membranous labyrinth
was normal and intact. The human macula utriculi was approached after
stapedectomy and irradiated with an argon laser in a patient who deve
loped persistent positional vertigo after closure of a perilymph fistu
la. Laser singular neurectomy was also done. Hearing remained unchange
d, and the patient's vertigo disappeared. The human macula sacculi, ho
wever, cannot be irradiated, because of the presence of pigment in the
saccular wall. In guinea pigs, the semicircular canals were irradiate
d from the outside. The lateral and posterior canals were approached t
hrough the middle ear, whereas the anterior canal was approached throu
gh the posterior fossa. Argon laser irradiation (1-1.5 W, 0.5 s) to th
e bony canal produced a charred area with or without perforation. The
semicircular duct showed shrinkage and tearing of the trabecular meshw
ork immediately after irradiation. Several weeks later, the canal had
been obliterated by ossification. Although laser labyrinthectomy can d
estroy the function of individual otolithic organs and eliminate dynam
ic impulses of the semicircular canals, hearing can be preserved.