We performed a prospective randomised study of two different sized per
cutaneous endoscopic gastrostomy (PEG) tubes to determine if tube size
influenced the incidence of PEG-related complications. Patients were
given prophylactic cefuroxime, if not already on antibiotics at the ti
me of PEG insertion. Fifty-two PEGs were successfully placed, 26 in ea
ch group. Most patients who required a PEG had suffered a cerebrovascu
lar event (82.7%). There were no procedure-related deaths. The mean ag
es (standard deviation) for the 12 and 20 French Gauge (FG) groups wer
e 78.7 (8.9) and 73.9 (14.4) years, respectively, with no statistical
difference. There were no significant differences in mortality (9 deat
hs in the 12 FG and 11 deaths in the 20 FG groups), number of peristom
al infections (8 infections in the 12 FG and 12 infections in the 20 F
G groups), episodes of leakage (12 leakages in the 12 FG and 17 leakag
es in the 20 FG groups) or tube blockage (2 blockage episodes in the 1
2 FG and 1 blockage episode in the 20 FG groups) between the two group
s over a follow-up period of 190 days. The incidence of insertion- and
feeding-related complications was thus not influenced by tube size. A
s the smaller PEG tubes were easier and less traumatic to insert we co
nclude that there are grounds for considering the more widespread use
of the narrower diameter 12 FG PEG tubes.