PREVALENCE OF HUMAN ASTROVIRUS SEROTYPE-4 - CAPSID PROTEIN-SEQUENCE AND COMPARISON WITH OTHER STRAINS

Authors
WILLCOCKS MM KURTZ JB LEE TW CARTER MJ
Citation
Mm. Willcocks et al., PREVALENCE OF HUMAN ASTROVIRUS SEROTYPE-4 - CAPSID PROTEIN-SEQUENCE AND COMPARISON WITH OTHER STRAINS, Epidemiology and infection, 114(2), 1995, pp. 385-391
Citations number
27
Categorie Soggetti
Infectious Diseases
Journal title
Epidemiology and infection → ACNP
ISSN journal
09502688
Volume
114
Issue
2
Year of publication
1995
Pages
385 - 391
Database
ISI
SICI code
0950-2688(1995)114:2<385:POHAS->2.0.ZU;2-W
Abstract
Astrovirus serotype 4 has increased in relative prevalence in the Oxfo rd, UK area in 1993. The structural gene of human astrovirus serotype 4 has been sequenced and the results indicate that this protein differ s substantially from serotypes 1 and 2. In particular, conservation at the C terminus is greatly reduced. However, amino acid substitutions in this region show a strong conservation in character suggesting that structural or functional constraints operate in this region.