The courses of spherical equivalent in patients (n = 62) who had mild,
non-cicatricial retinopathy of prematurity (ROP), and in those withou
t a history of ROP (n = 25) were modeled as a linear function of age;
an exponential model was also considered. A few (n = 5) without ROP ha
ve abnormal courses characterized by hyperopia in early infancy; none
have poor acuity. Although the majority of patients with ROP have cour
ses indistinguishable from those of term born controls, 27 (43.5%) hav
e abnormal courses, most of which are toward myopia. Optotype acuities
were significantly poorer among the ROP patients with abnormal than n
ormal refractive courses. Thus abnormal refractive development and acu
ity deficits are associated in eyes that have had mild ROP.