MUTISM DEVELOPING AFTER BILATERAL THALAMO-CAPSULAR LESIONS BY NEURO-BEHCET DISEASE

Authors
PARKMATSUMOTO YC OGAWA K TAZAWA T ISHIAI S TEI H YUASA T
Citation
Yc. Parkmatsumoto et al., MUTISM DEVELOPING AFTER BILATERAL THALAMO-CAPSULAR LESIONS BY NEURO-BEHCET DISEASE, Acta neurologica Scandinavica, 91(4), 1995, pp. 297-301
Citations number
22
Categorie Soggetti
Clinical Neurology
Journal title
Acta neurologica Scandinavica → ACNP
ISSN journal
00016314
Volume
91
Issue
4
Year of publication
1995
Pages
297 - 301
Database
ISI
SICI code
0001-6314(1995)91:4<297:MDABTL>2.0.ZU;2-E
Abstract
We described a 44-year old right-handed man showing mutism, left hemip legia and pseudobulbar palsy after CT and MRI documented bilateral tha lamo-capsular lesions by neuro-Behcet disease. Single photon emission tomography (SPECT) and Xenon CT revealed hypoperfusion of the bilatera l frontal lobes. The pathophysiological mechanism of mutism was discus sed and we postulate that mutism might occur as the result of frontal lobe dysfunction due to the disconnection of thalamocortical fiber fro m thalamus to frontal cortex and that it could be interpreted as an in complete form of akinetic mutism.