The purpose of this study is to assess the current strategy of mechani
cal circulatory support for profound heart failure. In the last 10 yea
rs, 37 patients with profound heart failure underwent mechanical circu
latory support after open heart surgery and 9 patients with non-cardio
tomy cardiogenic shock received emergency circulatory support. All pat
ients showed severe cardiac failure and/or fatal ventricular arrhythmi
a and required circulatory support as a life-saving measure. After car
diovascular surgery, 12 of those patients underwent venoarterial bypas
s (VAB), 13 had biventricular bypass (BVB), 8 had left ventricular byp
ass (LVB) and the remaining 4 patients received left ventricular assis
t device (LVAD). And 9 patients with non-cardiotomy cardiogenic shock
received percutaneous cardiopulmonary support (or PCPS) as an emergenc
y assist system. Weaning and discharge rates of the patients by the ty
pe of circulatory supports were 41.7% and 25.0% with VAB, 69.3% and 46
.2% with BVB, 87.5% and 37.5% with LVB, 75.0% and 50.0% with LVAD, and
44.4% and 11.1% with PCPS, respectively. Clinical results of postcard
iotomy circulatory support (64.9% of weaning and 37.8% of discharge) w
ere acceptable, but the patients with non-cardiotomy cardiac failure n
eeded early application of more advanced circulatory support.