ABSOLUTE-CONFIGURATION OF UROTHION, A PIGMENT OF URINE - ASYMMETRIC-SYNTHESIS OF 2-AMINO-6-(3,4-DIHYDROXYBUTYL)PTERIDIN-4(3H)-ONE THE DESULFURIZATION PRODUCT

Authors
SAKURAI A HORIBE H KUBOYAMA N HASHIMOTO Y OKUMURA Y
Citation
A. Sakurai et al., ABSOLUTE-CONFIGURATION OF UROTHION, A PIGMENT OF URINE - ASYMMETRIC-SYNTHESIS OF 2-AMINO-6-(3,4-DIHYDROXYBUTYL)PTERIDIN-4(3H)-ONE THE DESULFURIZATION PRODUCT, Tetrahedron letters, 36(15), 1995, pp. 2631-2632
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
15
Year of publication
1995
Pages
2631 - 2632
Database
ISI
SICI code
0040-4039(1995)36:15<2631:AOUAPO>2.0.ZU;2-I
Abstract
In order to determine the absolute configuration of urothion, ino-6-[( 3R)-3,4-dihydroxybutyl]-pteridin-4(3H)-one and its (3S) compound were synthesized. Comparing the CD spectra of their tri-4-chlorobenzoates w ith that derived from the natural product, R-configuration was conclud ed for the secondary hydroxyl group on the side chain of urothion.