ABSOLUTE-CONFIGURATION OF UROTHION, A PIGMENT OF URINE - ASYMMETRIC-SYNTHESIS OF 2-AMINO-6-(3,4-DIHYDROXYBUTYL)PTERIDIN-4(3H)-ONE THE DESULFURIZATION PRODUCT
A. Sakurai et al., ABSOLUTE-CONFIGURATION OF UROTHION, A PIGMENT OF URINE - ASYMMETRIC-SYNTHESIS OF 2-AMINO-6-(3,4-DIHYDROXYBUTYL)PTERIDIN-4(3H)-ONE THE DESULFURIZATION PRODUCT, Tetrahedron letters, 36(15), 1995, pp. 2631-2632
In order to determine the absolute configuration of urothion, ino-6-[(
3R)-3,4-dihydroxybutyl]-pteridin-4(3H)-one and its (3S) compound were
synthesized. Comparing the CD spectra of their tri-4-chlorobenzoates w
ith that derived from the natural product, R-configuration was conclud
ed for the secondary hydroxyl group on the side chain of urothion.