AMPLIFICATION OF THE MET GENE IN GLIOMA

Authors
FISCHER U MULLER HW SATTLER HP FEIDEN K ZANG KD MEESE E
Citation
U. Fischer et al., AMPLIFICATION OF THE MET GENE IN GLIOMA, Genes, chromosomes & cancer, 12(1), 1995, pp. 63-65
Citations number
17
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Genes, chromosomes & cancer → ACNP
ISSN journal
10452257
Volume
12
Issue
1
Year of publication
1995
Pages
63 - 65
Database
ISI
SICI code
1045-2257(1995)12:1<63:AOTMGI>2.0.ZU;2-K
Abstract
We have previously reported the finding of MET amplification linked to double minutes (dmins) in a human glioblastoma (TX3095). Because dmin s are found in approximately 50% of glioblastomas, 18 gliomas were ana lyzed For MET amplification. Three grade IV glioblastomas and one grad e II astrocytoma showed amplification. We could also localize the MET amplicon to dmins in glioblastoma TX3095 by fluorescence in situ hybri dization. (C) 1995 Wiley-Liss, Inc.