S. Nagahiro et al., THROMBOSED GROWING GIANT ANEURYSMS OF THE VERTEBRAL ARTERY - GROWTH-MECHANISM AND MANAGEMENT, Journal of neurosurgery, 82(5), 1995, pp. 796-801
Results in three patients with thrombosed giant aneurysms of the verte
bral artery are reported. Each of the aneurysms presented as a mass le
sion. On postcontrast computerized tomography and magnetic resonance i
maging, each aneurysm demonstrated a patent lumen and intrathrombotic
vascular channels. Two patients died and were autopsied, and the other
patient was successfully treated. Pathological examination revealed t
hat the aneurysms had staged clots, an open lumen, intrathrombotic cha
nnels with endothelial lining, and aneurysmal walls with intimal thick
ening. The authors suggest that the development of the intrathrombotic
capillary channels may be an important factor in the growth of thromb
osed giant aneurysm of the vertebral artery. Trapping of the aneurysm
followed by aneurysmectomy appears to be the best treatment for this t
ype of aneurysm.