Fourteen patients with common variable immunodeficiency (CVID) were st
udied. The common clinical manifestations were recurrent sore throat,
sinusitis, respiratory infections, diarrhea, and malnutrition. All had
low IgG, with normal cell-mediated Immunity. Treatment with immunoglo
bulin and/or plasma was effective In most of them. There were no sever
e adverse events with the therapy.