GROUP-A BETA-HEMOLYTIC STREPTOCOCCAL NECROTIZING FASCIITIS

There has been a recent flurry of interest in invasive group A beta he molytic streptococcal infections stimulated by sensational news report s in the British tabloids and by the news media in the United States. Such infections have been known throughout recorded history. The patho physiology and principles of treatment have been known for at least a century. The most effective antibiotic for treating this condition was discovered over fifty years ago and remains effective to this day. Al though these infections may be fatal within 24-48 hours, streptococcal necrotizing fasciitis is not a disease of medical progress, but is a disease not recognized because it has been made rare by the widespread use of antibiotics. A review of the pathophysiology and treatment of this condition is timely, however, as effective treatment requires imm ediate recognition, immediate surgical intervention, and prompt instit ution of antibiotic therapy.