ONLINE SOLID-PHASE EXTRACTION THERMAL-DESORPTION GAS-CHROMATOGRAPHY WITH ION-TRAP DETECTION TANDEM MASS-SPECTROMETRY FOR THE ANALYSIS OF MICROCONTAMINANTS IN WATER
Ajh. Louter et al., ONLINE SOLID-PHASE EXTRACTION THERMAL-DESORPTION GAS-CHROMATOGRAPHY WITH ION-TRAP DETECTION TANDEM MASS-SPECTROMETRY FOR THE ANALYSIS OF MICROCONTAMINANTS IN WATER, HRC. Journal of high resolution chromatography, 19(12), 1996, pp. 679-685
An improved set-up for solid-phase extraction with thermal desorption
coupled on-line to gas chromatography (SPETD-GC) is presented, It incl
udes a newly designed liner for a programmable temperature vaporizer B
TV) and an improved water elimination system, The SPETD procedure now
includes a washing step with HPLC-grade water to prevent degradation o
f analytes due to interaction with remaining sample constituents, The
system was used to analyze surface and tap water samples over a ii-mon
th period, No decrease of chromatographic or trace-enrichment performa
nce was observed, and a liner packed with Tenax GR could be used for a
t least 150 analyses, The SPETD module was coupled to GC,vith ion-trap
detection for mass spectrometric (MS) and MS/MS detection, The linear
ity and repeatability of the procedure for several pesticides which we
re tested in the 0.5-10 mu g/1 range were fully satisfactory (1 mu g/l
, RSD range 5-11%; n = 5), When using sample volumes of 0.1 ml only, d
etection limits were as low as 0.1-0.2 mu g/l. As an example, the conf
irmation and quantification of a suspected pesticide in a real-life sa
mple using electron impact and positive chemical ionization in both th
e MS and MS/MS mode is shown.