With AIDS has come a new level of T-cell immunosuppression, beyond tha
t previously seen. The impact of the HIV pandemic on the field of fung
al infections includes a major increase in the number of serious funga
l infections, an increase in the severity of those infections, and eve
n some entirely new manifestations of fungal illness. In this article
fungal pulmonary complications of AIDS are discussed. T-cell opportuni
sts including Cryptococcus neoformans and the endemic mycoses are the
most important pathogens. Phagocyte opportunists, including Aspergillu
s species and agents of mucormycosis, are less important.