INVESTIGATION ON THE REACTION OF INDOLYLB ORATE AND ITS USE FOR THE SYNTHESIS

This article deals with our recent results on the investigation of the reaction and synthetic application of trialkyl 2-indolylborate. (1)Hi gh regioselectivity on the reaction of the indolylborate with electrop hiles in the presence of copper(I) ion, highly depending on the nature of electrophiles used, was found. (2)Synthetic application of an intr amolecular alkyl migration process in the indolylborate for the constr uction of cyclo[1,2-a]and cyclo[1,2-b]indole systems was realized vie an intramolecular cyclization process. (3)Palladium catalyzed cross co upling, carbonylative cross coupling and tandem cyclization cross coup ling reactions with the indolylborate were developed and used for the preparation of indole derivatives.