Cytopathological characteristics of undifferentiated carcinoma of the
ovary were examined and reviewed. Seven cases of undifferentiated carc
inoma were encountered among 202 malignant ovarian neoplasms in the Sa
itama Cancer Center. Histologically, two cases contained a minor compo
nent of usual Mullerian carcinoma and five others were purely of solid
architecture without differentiation. Nevertheless, six cases, four o
f which were totally undifferentiated histologically, showed cytologic
al features characteristic of adenocarcinoma. The results indicate tha
t even carcinomas histologically diagnosed as undifferentiated may hav
e cytological features of glandular differentiation, which may be Mull
erian in origin. (C) 1995 Wiley-Liss, Inc.