TRANSFER OF 6 OR MORE EMBRYOS IMPROVES SUCCESS RATES IN PATIENTS WITHREPEATED IN-VITRO FERTILIZATION FAILURES

Objective: To examine the results of six or more embryos transferred t o patients whose IVF-ET cycles repeatedly met with failure. Design: Pr ospective clinical evaluation of pregnancy rates and pregnancy outcome . Setting: IVF-ET Unit. Patients: Seventy-two NF patients who had fail ed at least four previous IVF cycles. Interventions: Forty-one patient s (group A) received six or more embryos, and 31 patients (group B) ch ose to receive five embryos. Main Outcome Measures: Per embryo implant ation rate, pregnancy rate, multiple pregnancies, and outcome were eva luated. Results: With the transfer of six or more embryos, the pregnan cy rate was significantly higher than with the transfer of five embryo s (56% versus 29%, respectively). This was associated with a slight, b ut insignificant, increase in multiple gestations. No difference in pr egnancy outcome was noted among the groups. Conclusions: Patients who have had repeated IVF failures may have higher pregnancy rates if six or more embryos are transferred in subsequent cycles.