During the last few decades antibiotics have played an extremely impor
tant role in the management of otitis media (OM). Nowadays there are o
nly sporadic reports of its sequelae and complications in the develope
d countries. Nevertheless, complications of OM still arise and the pot
ential seriousness of this problem emphasizes the need for a high degr
ee of monitoring. We report herewith a case of acute mastoiditis in an
18-month-old infant with chronic suppurative otitis media (CSOM). Rep
eated cultures from the middle ear and mastoid cavity yielded Salmonel
la type C. The treatment modality and the pathophysiologic aspects are
discussed.