Jf. Gruden et al., AIDS-RELATED KAPOSI-SARCOMA OF THE LUNG - RADIOGRAPHIC FINDINGS AND STAGING SYSTEM WITH BRONCHOSCOPIC CORRELATION, Radiology, 195(2), 1995, pp. 545-552
PURPOSE: To determine the chest radiographic findings in patients with
tracheobronchial Kaposi sarcoma (KS) and to develop a radiographic st
aging system that allows comparison of radiographic to bronchoscopic f
indings and allows assessment of the typical temporal progression of p
ulmonary KS. MATERIALS AND METHODS: The chest radiographs and medical
records of 76 male patients, aged 23-60 years (mean, 36 years 4 months
) with bronchoscopically proved KS were retrospectively reviewed. Tumo
r extent at bronchoscopy (grade 1-3) was compared with severity of par
enchymal disease (radiographic stage 0-3). RESULTS: There was a statis
tically significant relationship between extent of tracheobronchial di
sease and radiographic stage (P =.01). However, in same patients, pare
nchymal KS of advanced stage was present with no visible endobronchial
disease. CONCLUSION: The proposed staging system describes features o
f early, moderate, and advanced KS. Although there is a correlation be
tween tracheobronchial and parenchymal disease, the latter can occur i
n the absence of endobronchial lesions.