The middle calves of the legs of 25 volunteers (12 men and 13 women, a
ged 18-25 years), as well as phantoms, were examined with 1.5-T magnet
ic resonance imaging. Gradient-recalled technique was combined with ma
gnetization transfer contrast (MTC) and chemical shift imaging. Period
ic oscillation of the MTC effect in fat tissue with variation of echo
time was identified at the frequency corresponding to the water-fat ch
emical shift difference.