THE EFFECT OF INJECTION TECHNIQUE ON THE PASSIVE SPREAD OF ASTROCYTESFOLLOWING TRANSPLANTATION INTO RAT SPINAL-CORD WHITE-MATTER

Authors
OLBY NJ OLEARY MT TARGETT MP BLAKEMORE WF
Citation
Nj. Olby et al., THE EFFECT OF INJECTION TECHNIQUE ON THE PASSIVE SPREAD OF ASTROCYTESFOLLOWING TRANSPLANTATION INTO RAT SPINAL-CORD WHITE-MATTER, Restorative neurology and neuroscience, 7(3), 1995, pp. 171-174
Citations number
19
Categorie Soggetti
Neurosciences
Journal title
Restorative neurology and neuroscience → ACNP
ISSN journal
09226028
Volume
7
Issue
3
Year of publication
1995
Pages
171 - 174
Database
ISI
SICI code
0922-6028(1995)7:3<171:TEOITO>2.0.ZU;2-O
Abstract
Bisbenzimide-labelled astrocytes were transplanted into the spinal whi te matter of the rat using three different injection techniques and th e variability of the longitudinal distance over which they were found was compared 30 min later. Cells spread up to 5.02 mm and the greatest variability was seen when they were injected as a bolus (54%), compar ed with 26% when injected over 2 min. These results show the importanc e of establishing the extent of passive spread of cells and its variab ility when performing studies in cell migration.