SOLUBILITY RETENTION RELATIONSHIPS IN SUPERCRITICAL-FLUID CHROMATOGRAPHY

The effects of temperature, pressure and supercritical fluid density o n solubility-retention relationship of solutes in supercritical fluid partition chromatography are investigated. New retention data for naph thalene and phenanthrene are obtained as a function of pressure at dif ferent temperatures. The mobile-phase partial molar volumes of the sol utes are determined from infinite-dilution fugacity coefficients and u sed to model the pressure dependence of solute retention that reveals the nature of interactions between the stationary phase and the solute . Relationships between pressure and temperature dependence of solubil ity and retention of solutes are also illustrated.