PERIODIC PACING AN IN-VITRO EPILEPTIC FOCUS

Authors
JERGER K SCHIFF SJ
Citation
K. Jerger et Sj. Schiff, PERIODIC PACING AN IN-VITRO EPILEPTIC FOCUS, Journal of neurophysiology, 73(2), 1995, pp. 876-879
Citations number
25
Categorie Soggetti
Neurosciences,Physiology,Neurosciences,Physiology
Journal title
Journal of neurophysiology → ACNP
ISSN journal
00223077
Volume
73
Issue
2
Year of publication
1995
Pages
876 - 879
Database
ISI
SICI code
0022-3077(1995)73:2<876:PPAIEF>2.0.ZU;2-H
Abstract
1. The effects of frequency of orthodromic and antidromic stimulation of CA3 on formation of electrographic seizurelike discharges in CA1 wa s studied in the high potassium hippocampal slice. 2. Within the range of stimulation of CA3 used, 0.1-10.0 Hz, a narrow range was identifie d between 1.0 and 1.3 Hz, where the tonic phase of seizure generation in CA1 was suppressed. This suppression was observed for both Schaffer collateral and messy fiber stimulation.