B. Zdolsek et al., VAGINAL MICROBIOLOGICAL FLORA AND SEXUALLY-TRANSMITTED DISEASES IN WOMEN WITH RECURRENT OR CURRENT VULVO-VAGINAL CANDIDIASIS, Infection, 23(2), 1995, pp. 81-84
A history of recurrent vulvovaginal candidiasis (RVVC) was reported by
102 women, while current vulvovaginal candidiasis (VVC) was diagnosed
in 83 of the same 996 women, They had all attended two family plannin
g and one youth clinic, respectively. Two women, without RVVC or VVC,m
atched for age for each case of RVVC, were selected as a comparison gr
oup (COMP). Recurrent, but not current VVC, was associated with a hist
ory of sexually transmitted disease, Those with current, but not with
recurrent, VVC had significantly more often genital warts and bacteriu
ria (> 10(5) bacteria/ml), but significantly less often bacterial vagi
nosis than the COMP women, Both VVC and RVVC were inversely correlated
to a vaginal nora change with a mixed anaerobic vaginal flora. Those
with VVC had a greater number of lactobacilli on vaginal cultures, tha
n those with RVVC and the women in the COMP group. VVC and a history o
f RVVC both occurred more frequently in women with a lactobacilli-pred
ominated vaginal flora, as compared with those with a nora change with
a mixture of anaerobic and facultative anaerobic bacteria.