Infection,vith Epstein-Barr virus (EBV) is common and induces a broad
spectrum of illness. In the majority-of cases the disease manifests wi
th typical signs of heterophile-positive infectious mononucleosis in w
hich myalgia may be seen in up to 20% of cases. In this study, a case
of rhabdomyolysis is reported occurring during the clinical course of
an 18-year-old patient with infectious mononucleosis. This severe form
of muscle involvement has been rarely associated with EBV infections.
Five similar cases previously published in the English literature are
also reviewed. The clinical implications of rhabdomyolysis and infect
ious mononucleosis are discussed.