COAGULOPATHY WITH PIPERACILLIN ADMINISTRATION IN CYSTIC-FIBROSIS - 2 CASE-REPORTS

Two cases are reported of coagulopathy in association with the adminis tration of piperacillin to patients with cystic fibrosis. In both case s the coagulopathy was associated with the development of a serum sick ness-like illness with fever, rash and abnormal liver function tests o ccurring on day 12 and day 16 of treatment, respectively. On withdrawa l of the piperacillin, both the serum sickness and the coagulopathy re solved rapidly without sequelae.