ASSIGNMENT OF BORRELIA-BURGDORFERI STRAINS G25 AND VS461 TO THE BORRELIA-GARINII AND BORRELIA-AFZELII GENOSPECIES, RESPECTIVELY - A COMPARISON OF OSPA PROTEIN SEQUENCES

Authors
GODFROID E BENMESSAOUD A POLISZCZAK A LOBET Y BOLLEN A
Citation
E. Godfroid et al., ASSIGNMENT OF BORRELIA-BURGDORFERI STRAINS G25 AND VS461 TO THE BORRELIA-GARINII AND BORRELIA-AFZELII GENOSPECIES, RESPECTIVELY - A COMPARISON OF OSPA PROTEIN SEQUENCES, DNA sequence, 5(4), 1995, pp. 251-254
Citations number
16
Categorie Soggetti
Biothechnology & Applied Migrobiology","Genetics & Heredity
Journal title
DNA sequence → ACNP
ISSN journal
10425179
Volume
5
Issue
4
Year of publication
1995
Pages
251 - 254
Database
ISI
SICI code
1042-5179(1995)5:4<251:AOBSGA>2.0.ZU;2-A
Abstract
The nucleotide sequence encoding the Outer Surface Protein A (OspA) fr om two Borrelia burgdorferi sensu late isolates, G25 and VS461, has be en determined. On the basis of a phylogenetic analysis, strains G25 an d VS461 were respectively assigned to the B. garinii and B. afzelii ge nospecies. Comparative analysis of OspA proteins from 26 different B. burgdorferi sensu late strains involved in Lyme disease indicated a hi gher heterogeneity in the B. garinii genospecies than in the two other genospecies, B. burgdorferi sensu stricto and B. afzelii.