POLYHYDRAMNIOS AND HYPERCALCEMIA ASSOCIATED WITH CONGENITAL MESOBLASTIC NEPHROMA - CASE-REPORT AND A NEW APPRAISAL

Background: Polyhydramnios and hypercalcemia are known complications o f congenital mesoblastic nephroma. Hypercalcemia has been shown to cau se polyuria. Polyuria is believed to be the probable cause for the pol yhydramnios, but the exact mechanism remains unknown. To our knowledge , this is the first reported ease of a relationship between hypercalce mia and polyhydramnios. Case: A 26-year-old primigravida was diagnosed with congenital mesoblastic nephroma and polyhydramnios at 36 weeks' gestation. Neonatal hypercalcemia was detected immediately after deliv ery at 40 weeks' gestation. After removal of the nephroma, the calcium level normalized. Conclusion: Hypercalcemia may be the mechanism unde rlying polyhydramnios in cases of congenital mesoblastic nephroma. Cal cium levels should be monitored after delivery, and prompt surgical re moval of the tumor should be performed.