DALDA (H-TYR-D-ARG-PHE-LYS-NH2), A POTENT MU-OPIOID PEPTIDE AGONIST, AFFECTS VARIOUS PATTERNS OF LOCOMOTOR ACTIVITIES

Authors
MEYER ME MCLAURIN BI MEYER ME
Citation
Me. Meyer et al., DALDA (H-TYR-D-ARG-PHE-LYS-NH2), A POTENT MU-OPIOID PEPTIDE AGONIST, AFFECTS VARIOUS PATTERNS OF LOCOMOTOR ACTIVITIES, Pharmacology, biochemistry and behavior, 51(1), 1995, pp. 149-151
Citations number
11
Categorie Soggetti
Pharmacology & Pharmacy","Pharmacology & Pharmacy
Journal title
Pharmacology, biochemistry and behavior → ACNP
ISSN journal
00913057
Volume
51
Issue
1
Year of publication
1995
Pages
149 - 151
Database
ISI
SICI code
0091-3057(1995)51:1<149:D(APMP>2.0.ZU;2-Z
Abstract
The central effects of mu-opioid receptor agonist DALDA (ICV 0.00, 0.1 , or 1.0 mu g) were investigated in rats for 120 min on activity monit ors. The durations in seconds of horizontal. movement time, rearing ti me, and stereotypy time were measured during 12 consecutive 10-min tim e blocks. DALDA (ICV, 0.1 and 1.0 mu g) resulted in biphasic effects, inhibition followed by activation for horizontal movement, rearing, an d stereotypy times.