ULCERATIVE TYPE OF COLITIS ASSOCIATED WITH THE USE OF HIGH-STRENGTH PANCREATIC-ENZYME SUPPLEMENTS IN CYSTIC-FIBROSIS

A 2 1/2-year-old girl with cystic fibrosis, who presented with hematoc hezia, developed an inflammatory ulcerative type of colitis with mild interstitial fibrosis and colonic narrowing while being treated with h igh strength pancreatic enzyme supplements. Findings of contrast enema , endoscopy, and colonic biopsy are described. The spectrum of colonic disease associated with the use of high strength pancreatic enzyme su pplements cystic fibrosis patients is discussed.