Cj. Eagles et al., NONPHARMACOLOGICAL MODIFICATION OF CARDIAC RISK-FACTORS .1., Journal of clinical pharmacy and therapeutics, 21(5), 1996, pp. 289-296
Many factors influence whether a person will develop coronary heart di
sease. Genetic predisposition, gender and advanced age are recognized
risk factors for the development of coronary heart disease over which
we have little control. On the other hand, high serum cholesterol, cig
arette smoking, high blood pressure, excessive body weight and long-te
rm physical inactivity are key risk factors over which we have conside
rable control. In many cases cardiac risk factors can be modified with
out resorting to pharmacological intervention. Current evidence sugges
ts that individuals who follow a diet which is low in saturated fats a
nd cholesterol, lose weight, stop cigarette smoking and take regular a
erobic exercise will significantly reduce their risk of developing cor
onary heart disease. In addition, patients who already have evidence o
f coronary heart disease may improve their symptoms and prognosis by s
imilar life-style changes. In the first of two parts, we review the ro
le of exercise in modifying cardiac risk factors.