RELATIONSHIP BETWEEN CONCURRENT SUBSTANCE-ABUSE IN PSYCHIATRIC-PATIENTS AND NEUROLEPTIC DOSAGE

Citation
Da. Dmello et al., RELATIONSHIP BETWEEN CONCURRENT SUBSTANCE-ABUSE IN PSYCHIATRIC-PATIENTS AND NEUROLEPTIC DOSAGE, The American journal of drug and alcohol abuse, 21(2), 1995, pp. 257-265
Citations number
31
Categorie Soggetti
Substance Abuse","Psycology, Clinical
ISSN journal
00952990
Volume
21
Issue
2
Year of publication
1995
Pages
257 - 265
Database
ISI
SICI code
0095-2990(1995)21:2<257:RBCSIP>2.0.ZU;2-Z
Abstract
The use of a structured diagnostic interview (The Schedule for Affecti ve Disorders and Schizophrenia) with 58 consecutively admitted general adult psychiatric patients revealed that 62.1% of them abused alcohol and 58.6% had a substance use disorder. The drug abusers did not diff er significantly from the nonabusers on mean psychoticism (Brief Psych iatric Rating Scale) scores. However, they received higher doses of an tipsychotic agents (mean daily dose 1022 mg CPZ EQ (SD = 614) vs 609 m g CPZ EQ (SD = 481); z = 2.58, p < .01) to achieve stabilization. The clinical implications of this finding are discussed.