HEMODYNAMIC EVALUATION OF A NEW BILEAFLET VALVE PROSTHESIS - AN ACUTEANIMAL EXPERIMENTAL-STUDY

Background and aims of the study: A newly developed heart valve (Medtr onic Parallel(TM)) was tested in an acute animal experimental model. M ethods: Five prototype valves were implanted in the aortic position in seven 90 kg pigs to enable acute evaluation of the hemodynamic perfor mance in terms of turbulent stresses and transvalvular pressure drop. Turbulent stresses in the ascending aorta were measured using a 10 MHz perivascular Doppler echocardiographic transducer designed to measure the radial velocity component at 17 different points covering the aor tic cross- sectional area. Results: The drop in transvalvular peak pre ssure measured with fluid-filled catheters showed a non-linear relatio nship with cardiac output and was always <12 mmHg. The Reynolds normal stresses were <60 N/m(2) in systole within 50 ms time windows, which is insufficient to cause mechanical damage of the formed elements of t he blood. Conclusions: From a hemodynamic point of view the performanc e of the Medtronic Parallel aortic valve is fully acceptable and withi n the range of other similar, currently available mechanical valves.