QUANTITATIVE-ANALYSIS OF THE ELECTROENCEPHALOGRAM IN THE INTRACAROTIDAMOBARBITAL PROCEDURE .2. COHERENCE ANALYSIS

Thirty-seven subjects underwent bilateral internal carotid artery inje ctions of amobarbital before surgery for intractable epilepsy. The ele ctroencephalograms (EEG) of these patients were continuously monitored during these 74 procedures and were later subjected to quantitative a nalysis. Analysis of interhemispheric coherence in the delta, theta, a lpha, and beta 1 bands was performed. Prominent changes occurred in in terhemispheric coherence, which showed a precipitous drop in the first 2 min after amobarbital injection, followed by a gradual return to ne ar baseline levels. These results suggest that interhemispheric relati onships are significantly disrupted by intracarotid amobarbital inject ion.