A CASE OF BONE-MARROW RECURRENCE FROM GASTRIC-CARCINOMA AFTER A 9-YEAR DISEASE-FREE INTERVAL

We present a case of very fate and unusual recurrence of gastric cance r. Nine years following total gastrectomy for gastric carcinoma, a 57- year-old man presented with disseminated intravascular coagulation ass ociated with hone marrow recurrence. The primary tumor was a signet ri ng cell carcinoma invading the subserosal layer with lymph node metast asis. The patient wits treated with sequential administration of metho trexate and 5-fluorouracil and went into remission, After treatment, h e survived 10 months. Autopsy revealed diffuse bone marrow infiltratio n and distant lymph node metastasis with signet ring carcinoma cells.