SYNTHESIS OF 8-METHYLNONANOL, A COMMON INTERMEDIATE FOR DIHYDROCAPSAICIN AND FRESH-WATER MUSSEL COMPONENT

Authors
HASSARAJANI SA MITHRAN S MAMDAPUR VR
Citation
Sa. Hassarajani et al., SYNTHESIS OF 8-METHYLNONANOL, A COMMON INTERMEDIATE FOR DIHYDROCAPSAICIN AND FRESH-WATER MUSSEL COMPONENT, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 34(5), 1995, pp. 429-431
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
34
Issue
5
Year of publication
1995
Pages
429 - 431
Database
ISI
SICI code
0376-4699(1995)34:5<429:SO8ACI>2.0.ZU;2-H
Abstract
An efficient synthesis of 8-methylnonanoic acid (6), a synthon of dihy drocapsaicin (1) and 14-methylpentadec-6(Z)-enoic acid (2) which is a component of fresh water mussel, is accomplished from a common interme diate, 8-methylnonanol (3). Grignard coupling, oxidation and/or Wittin g olefination are the key features in these approaches.