L. Pierro et al., CORRELATION OF LENS THICKNESS WITH BLOOD-GLUCOSE CONTROL IN DIABETES-MELLITUS, Acta ophthalmologica Scandinavica, 74(6), 1996, pp. 539-541
The aim of this study was to verify if lens thickness in insulin-depen
dent diabetic patients is greater than in non-diabetics, and to establ
ish which parameters affect the thickness of the lens age, diabetes du
ration, glycaemic control, insulin dose. Ultrasound biometry and blood
glucose measurements were taken in 87 patients three times a day: fas
ting 2 and 4 h after lunch. The patient sample was divided into three
groups: 30 with no retinopathy, 30 presented background retinopathy an
d 27 with proliferative retinopathy; 30 normal subjects with a similar
age to the diabetic group, comprised the control group. No correlatio
n was found between biometric values and blood glucose in the three gr
oups (p>0.05). A significant difference in lens thickness was found in
the four groups, even after adjusting for age (p < 0.05). Significant
differences in lens thickness were seen between proliferative retinop
athy and the other groups, after adjusting for age and duration of dia
betes (p < 0.05); lens thickness was shown to correlate with diabetes
duration (p < 0.05).