NEUROTOXIC EFFECTS OF COBRA VENOM (NAJA-H AJE-HAJE) ON NEUROMUSCULAR-JUNCTION - A CLINICO-ELECTROMYOGRAPHIC STUDY OF 2 CASES IN TUNISIA

Authors
ZOUARI N CHOYAKH F
Citation
N. Zouari et F. Choyakh, NEUROTOXIC EFFECTS OF COBRA VENOM (NAJA-H AJE-HAJE) ON NEUROMUSCULAR-JUNCTION - A CLINICO-ELECTROMYOGRAPHIC STUDY OF 2 CASES IN TUNISIA, Neurophysiologie clinique, 25(2), 1995, pp. 59-65
Citations number
16
Categorie Soggetti
Neurosciences,Physiology
Journal title
Neurophysiologie clinique → ACNP
ISSN journal
09877053
Volume
25
Issue
2
Year of publication
1995
Pages
59 - 65
Database
ISI
SICI code
0987-7053(1995)25:2<59:NEOCV(>2.0.ZU;2-H
Abstract
Two patients were bitten by tunisian cobras (Naja haje haje). A few ho urs after the bite they developped generalized paralysis wich progress ed to respiratory paralysis. Electrophysiological features are similar to those of myasthenia gravis and exhibit decremental pattern after s timulation at a frequency of three per second. It is probable that cob ra neurotoxins act postsynaptically. The neuromuscular blocking activi ty of snake-venom can be reversed by intravenous neostigmine.