C. Geretsegger et al., IPSAPIRONE IN THE TREATMENT OF BULIMIA-NERVOSA - AN OPEN PILOT-STUDY, The International journal of eating disorders, 17(4), 1995, pp. 359-363
Seventeen women who met the criteria for bulimia nervosa (DSM-III-R) w
ere treated for 4 weeks in an open trial with ipsapirone, a partial 5-
HT1A agonist. Bulimic symptoms diminished in 66.6% of the patients aft
er only 1 week of treatment, 93.3% showed a reduction of more than 50%
of weekly binge eating attacks after 4 weeks. The mean frequency of b
inges was reduced by 81% at endpoint. Ipsapirone was well tolerated. (
C) 1995 by John Wiley and Sons, Inc.