T. Humbert et al., IMMUNOLOGICAL CHANGES IN A CASE OF MARCHIAFAVA-BIGNAMI DISEASE - RESPONSE TO AMINEPTINE TREATMENT, European psychiatry, 10(2), 1995, pp. 107-109
Marchiafava-Bignami disease (MBD) is a rare complication of chronic al
coholism. We describe a regressive form of MBD in which a primary decr
ease in CD4(+) cells was improved by amineptine treatment. No signific
ant change in the CD4 : CD8 ratio was observed in a few major depresse
d subjects receiving this drug.