NARCOLEPSY ASSOCIATED WITH ARTERIOVENOUS MALFORMATION OF THE DIENCEPHALON

Narcolepsy associated with localized brain lesions is rare, and few re ports of well-documented cases have been published. We describe the ca se of a 20-year-old male (HLA DQw1 negative) who fulfilled clinical an d polygraphic criteria of symptomatic narcolepsy. Narcolepsy in this p atient was associated with an arteriovenous malformation involving the structures around the third ventricle. Clinical symptoms improved aft er embolization and radiosurgery. These findings support the hypothesi s that lesions in the vicinity of the third ventricle can cause sympto matic narcolepsy.