Twenty-four-hour polysomnographic recordings were obtained during asym
ptomatic (ASP) and symptomatic (SP) periods in a patient with periodic
hypersomnia. During both periods, an abnormal sleep architecture was
detected, with a greater sleep fragmentation during the SP. An unexpec
ted finding was a shortening of the latency of slow-wave sleep, with a
difference of more than 5 hours between the ASP and the SP. The great
er fragmentation of rapid eye movement sleep during the SP may suggest
a disorganization of the ultradian rhythm of rapid eye movement sleep
.