The clinical importance of gastrointestinal disorders among patients w
ith acquired immunodeficiency syndrome (AIDS) is enormous. Estimates o
f gastrointestinal complaints among AIDS patients range from 30% to 90
%. Many of these patients may be chronically ill and have multiple sim
ultaneous opportunistic pathogens and neoplasms. The diagnosis and man
agement of serious gastrointestinal complications that often occur in
the setting of chronic illness represent major challenges in the care
of patients with AIDS.