REGIONAL CEREBRAL OXYGEN-SATURATION DURING INTRAARTERIAL PAPAVERINE THERAPY FOR VASOSPASM - CASE-REPORT

Citation
Ms. Luer et al., REGIONAL CEREBRAL OXYGEN-SATURATION DURING INTRAARTERIAL PAPAVERINE THERAPY FOR VASOSPASM - CASE-REPORT, Neurosurgery, 36(5), 1995, pp. 1033-1036
Citations number
17
Categorie Soggetti
Surgery,Neurosciences
Journal title
ISSN journal
0148396X
Volume
36
Issue
5
Year of publication
1995
Pages
1033 - 1036
Database
ISI
SICI code
0148-396X(1995)36:5<1033:RCODIP>2.0.ZU;2-0
Abstract
CEREBRAL ARTERIAL VASOSPASM continues to be a major secondary medical complication of aneurysmal subarachnoid hemorrhage. Despite hypervolem ic hemodilution, arterial hypertension, and pharmacological therapy, m orbidity and mortality due to vasospasm remain high. The authors discu ss a patient with vasospasm who did not respond to traditional medical therapy and who underwent intra-arterial papaverine infusions while b eing monitored with transcranial cerebral oximetry. Oximetry during th e procedure revealed significant improvements in brain regional satura tion of oxygen, with the relief of vasospasm that correlated with clin ical improvements in the patient's neurological status. Transcranial c erebral oximetry was used to monitor regional oxygen saturation throug hout the angiographic and interventional procedures, providing continu ous, real-time, clinically relevant information about the effects of v asospasm and its treatment.