CIRCULATING IMMUNE-COMPLEXES IN INTRACRANIAL NEOPLASMS

The levels of circulating immune complexes (CIC) were assayed in the s era of 109 patients with intracranial space occupying lesions. The CIC levels were significantly increased in all the brain tumours. After t reatment, the CIC levels were still significantly increased when compa red to the controls but showed no change when compared to their respec tive pre-operative values. Further, no change was observed in the CIC levels between the malignant and benign tumour case. Moreover, in brai n tumours, 90% of the CIC precipitate consisted of IgG. However, the C IC levels fail to prognosticate the process of the disease in these pa tients.